Isolation and characterization of interferon lambda-resistant hepatitis C virus replicon cell lines
نویسندگان
چکیده
منابع مشابه
Effect of alpha interferon on the hepatitis C virus replicon.
Chronic hepatitis C virus (HCV) infections can be cured only in a fraction of patients treated with alpha interferon (IFN-alpha) and ribavirin combination therapy. The mechanism of the IFN-alpha response against HCV is not understood, but evidence for a role for viral nonstructural protein 5A (NS5A) in IFN resistance has been provided. To elucidate the mechanism by which NS5A and possibly other...
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ژورنال
عنوان ژورنال: Virology
سال: 2013
ISSN: 0042-6822
DOI: 10.1016/j.virol.2013.07.005